Clinical Eligibility & Testing

Talk to your doctor about using the Oncotype DX Genomic Prostate Score (GPS) and whether it’s right for you. If your doctor orders the test, no additional procedures are needed—samples from your most recent biopsy will be analyzed to provide information on the aggressiveness of your tumor.

Is the test right for you?

You could be eligible for the Oncotype DX GPS test if you have:

Prostate biopsy within the last three years

NCCN® very low-, low-, or intermediate-risk prostate cancer

No definitive treatment for prostate cancer

NCCN® very low-, low-, or intermediate-risk prostate cancer means1:

  • Your blood levels of prostate-specific antigen (PSA), a protein produced in the prostate gland, are less than 20 ng/mL.
  • Your Gleason score, an estimate of prostate cancer aggressiveness based on how the cancer looks under a microscope, is 3+3, 3+4 or 4+3.
  • The stage of your tumor is T1c or any T2.

If you don’t know these numbers or are not sure, ask your doctor, or request a copy of your pathology report.

Three simple steps to get the test

With your Genomic Prostate Score, you and your doctor will have the information you need to create a plan that is right for you.



The Oncotype DX GPS test is conducted on a small tissue sample already taken from your most recent biopsy.


About 2 weeks after your biopsy arrives at the Exact Sciences laboratory, your GPS result will be available to your doctor. Your results will include your level of risk for prostate cancer death and metastasis within 10 years after surgery, as well as your risk for adverse pathology.*


You and your doctor can use your results to help understand your options and discuss what's next for you.

The Oncotype DX GPS test is covered by Medicare (for eligible patients with NCCN Very Low-, Low-, and Intermediate-risk prostate cancer). Private insurance coverage varies.


* Adverse pathology will not be reported for Gleason 4+3 patients due to the aggressive nature of their disease.

1. NCCN Clinical Practice Guidelines in Oncology: Prostate Cancer. V.2.2020.

National Comprehensive Cancer Network (NCCN) and NCCN are registered trademarks of NCCN. NCCN does not endorse any product or therapy.

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