Each case of prostate cancer is unique. It’s important for you and your doctor to explore the management option that addresses your situation and can most effectively manage your health. The results from the Oncotype DX Genomic Prostate Score (GPS Report) can help you and your doctor better understand the likelihood of aggressive disease, which can help make decisions about how to treat your cancer.
Has Your Doctor Ordered Oncotype DX for you?
Watch this video to understand how Oncotype DX can help with your cancer treatment decision.
Understanding your score
Use our patient report overview to explain the Oncotype DX GPS test results.
What can you learn from your test results?
Watch this video to prepare for your Oncotype DX test results and discuss next steps with your doctor.
The GPS Result is a score between 0 and 100 that measures the activity (expression) of certain genes within the tumor. In the example above, the patient has a GPS result of 15, consistent with very low-risk cancer.
Your Individualized Level of Risk
Your report will also include clinical endpoints that further define your individual risk.
- Prostate cancer death: In the sample report above, the risk of prostate cancer death within 10 years is <1%.
- Metastasis: The risk of metastasis (cancer spreading beyond the prostate) within 10 years after surgery is shown in this example to be 1%.
- Adverse pathology: The risk of aggressive disease is shown in this example as 18%.
How to use the results
Once you have the results, you and your doctor can use the GPS test to aid in discussions about your treatment options and help make a treatment plan. Treatment plans often consider things like:
- Your doctor’s assessment of your overall cancer risk, taking into account biopsy, PSA, GPS, etc.
- Your age, overall health, and lifestyle.
For example, the higher your GPS, the more likely it is that your cancer is aggressive and needs immediate treatment such as surgery or radiation therapy. While effective at treating aggressive cancers, surgery and radiation therapy can cause long-lasting side effects.
The lower your GPS, the less likely it is that your cancer is aggressive and needs immediate treatment. Through a program of regular check-ups and tests known as active surveillance, you might delay or even avoid side effects of immediate treatment.
Active surveillance is a proactive treatment strategy to closely monitor and follow your cancer—if any changes are detected, you and your physician can immediately discuss alternative treatment options.